As more and more variants are emerging, CTK’s commitment to ensure that CTK’s OnSite® COVID-19 Ag Rapid Test isn’t affected by these mutations is ongoing.
We analyzed the NP mutations present in the California, Nigeria, and India/Delta variants and mapped them on the SARS-CoV-2 NP protein recognized by CTK’s OnSite® COVID-19 Ag Rapid Test using ELISA and peptide scanning. We found that the mutations and deletions of these new variants (California, Nigeria, and India/Delta) do not fall within the epitopes recognized by the conjugate and capture antibodies used in CTK’s OnSite® COVID-19 Ag Rapid Test.
CTK’s OnSite® COVID-19 Ag Rapid Test is not impacted by the mutations from the California, Nigeria, and India/Delta variants. By continuing to surveil and analyze if new variants have mutations within the two antibodies’ epitopes, we are able to predict the impact of any mutations on the detection performance of CTK’s OnSite® COVID-19 Ag Rapid Test.
To read the white paper, click here
To read “CTK’s OnSite Covid-19 Ag Rapid Tests detect newly identified U.K., South Africa, and Brazil SARS-CoV-2 variants” , click here
References
Zhang, L, Zhang, B, Lorenzo, L, Ridin, A, Liberal, V. (2021). OnSite Covid-19 Ag Rapid Tests detect new SARS-CoV-2 variants, including U.K., South Africa, Brazil, California, Nigeria and India/Delta variants [White paper]. CTK Biotech.