Mouse Anti-human IgM Monoclonal Antibody

Human IgM is one of several forms of antibody that are produced by human B cells. Mainly produced in the spleen, IgM is the largest antibody formed as a pentamer, with a molecular weight of 970kDa.

It is the first antibody to appear in the response to initial exposure to a pathogen/antigen. The detection of pathogen-specific IgM antibodies has served as a useful tool for diagnosis of early microbial infections.

B0007 was generated by immunizing mice with human IgM and purified from ascites via protein A affinity chromatography. It recognizes the Fc portion of human IgM.

  • Physical                                                 Liquid
  • Concentration                           ≥ 2 mg/mL by OD280 nm
  • Storage Buffer                           D-PBS, pH 7.2-7.4
  • Preservatives                              0.099% NaN3
  • Purity                                                           ≥ 95% on 12.5% SDS-PAGE
  • Purification                                      Protein A affinity chromatography
  • Application                                      Coating or conjugate antibody in ELISA, ICT, and other immunoassays
  • Cross Reactivity                     No reactivity with human IgG and IgA