Mouse Anti-human IgM Monoclonal Antibody
Human IgM is one of several forms of antibody that are produced by human B cells. Mainly produced in the spleen, IgM is the largest antibody formed as a pentamer, with a molecular weight of 970kDa.
It is the first antibody to appear in the response to initial exposure to a pathogen/antigen. The detection of pathogen-specific IgM antibodies has served as a useful tool for diagnosis of early microbial infections.
B0007 was generated by immunizing mice with human IgM and purified from ascites via protein A affinity chromatography. It recognizes the Fc portion of human IgM.