The Aridia Chikungunya Real-Time PCR Test is based on the real time amplification and detection of chikungunya virus (CHIKV) RNA in a one-step format.
The test is designed for specific and qualitative detection of CHIKV RNA in clinical specimens as an aid in the diagnosis of acute CHIKV infection alongside all available clinical and epidemiological data, patient history, and other laboratory test outcomes. The product is intended for use by professionals specifically trained in nucleic acid amplification techniques and in vitro diagnostic procedures.
Recommended for use:
Any person presenting with clinical signs or symptoms within a week consistent with acute dengue infection or dengue fever including: high fever, maculopapular rash, myalgia, headaches, vomiting and nausea, and conjunctivitis.
As a subset of the acute clinical symptoms of CHIKV infection are also prevalent in Zika and dengue virus infections that are transmitted by the same mosquito vector, confirmatory diagnosis using real-time PCR is recommended for patients exhibiting clinically compatible symptoms to guide patient management decisions.
CHIKV RNA is detectable in serum up to 7 days post symptom onset. A positive PCR test during this detection window is confirmatory of CHIKV infection. A negative PCR test does not exclude infection as viremia decreases over time and must be followed up with serological testing.