Mouse Anti-Pan Dengue NS1 Monoclonal Antibody

Mouse Anti-Pan Dengue NS1 Monoclonal Antibody

Dengue virus (DENV) is a single positive strand RNA virus of the Flaviviridae family and a causative agent of the infectious tropical disease Dengue Fever. There are four serotypes of the virus, DENV-1, DENV-2, DENV-3 and DENV-4.

Dengue NS1 (Non-Structural protein 1) is a versatile glycoprotein of the dengue virus that is secreted as a hexamer, binds to the cell surface, and has immune evasive functions. Dengue virus NS1 antigen is also used as an early detection marker (days 1 to 9 after onset) for dengue virus infection.

B7140 was generated by immunizing mice with recombinant DENV-2 NS1 expressed by human cells and purified from cell culture via protein A affinity chromatography. It recognizes all 4 types of DENV NS1.

  • Physical                                                 Liquid
  • Concentration                   ≥ 2 mg/mL by OD280 nm
  • Storage Buffer                           D-PBS, pH 7.2-7.4
  • Preservatives                     0.09% NaN3
  • Purity                                         ≥ 95% on 12.5% SDS-PAGE
  • Purification                                      Protein A affinity chromatography
  • Application                                      Coating or conjugate antibody in ELISA, ICT, and other immunoassays for paring with B7060
  • Cross Reactivity                     No reactivity with Zika virus NS1
  • Shelf Life                                 24 months
  • Storage                                     2-8°C
  • Shipping                                  Shipped with Ice Pad (~4°C) in styrofoam box
  • Bio-safety                              This product does not originate from humans, and does not contain infectious agents such as HIV, HCV, and HBV.